Laser Guns are prominent weapons used throughout Dexter's Laboratory. The majority of laser guns seen were invented by Dexter while others are the work of Mandark, aliens or certain villains in the The Justice Friends or Dial M for Monkey shorts.
- Maternal Combat
- Orgon Grindor
- Ultrajerk 2000
- Aye Aye Eyes
- The Continuum of Cartoon Fools
- A Mandark Cartoon
- Ego Trip
- In "Aye Aye Eyes", Dexter implies that he keeps his guns in a 'Laserium' (combination of Laser and Emporium).